Genetic testing and counseling for hereditary forms of colorectal cancer
β Scribed by Gloria M. Petersen; Jill D. Brensinger; Karen A. Johnson; Francis M. Giardiello
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 189 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
We thank Ms. Jeanne Wenger and Ms. Linda M. Welch for secretarial assistance.
π SIMILAR VOLUMES
Lynch syndrome, or hereditary nonpolyposis colon cancer (HNPCC), is an autosomaldominant disease accounting for approximately 1 5 % of all colorectal cancer cases. Due to the lack of pathognomonic morphological or biomolecular markers, HNPCC has traditionally posed unique problems to clinicians and
The aim of this prospective study was to assess the uptake of predictive genetic testing for hereditary non-polyposis colorectal cancer (HNPCC) and its associations with sociodemographic and other factors, and long-term satisfaction with taking the test. The test was offered to all high-risk members
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most common hereditary form of colorectal carcinoma (CRC) and may account for 5-10% of the total CRC burden. The discovery of DNA mismatch repair (MMR) genes, inclusive of hMSH2, hMLH1, hPMS2, and hMSH6, has enabled the identification of wh
Hereditary nonpolyposis colorectal cancer (Lynch syndrome) is an autosomal dominant disease caused by mutations in the mismatch repair genes in particular in MLH1, MSH2 and MSH6. The disease is characterized by the development of colorectal, endometrial cancer and several other cancers. There is evi
Hereditary cancer represents approximately 5-10% of the total cancer burden and may account for 60,000 to 120,000 new cancer occurrences this year in the United States. New developments in molecular genetics and the cloning of cancer-prone genes have intensely fueled interest in dealing with heredit