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Acceleration of chromosomal instability by loss of BRCA1 expression and p53 abnormality in sporadic breast cancers

✍ Scribed by Yasuo Miyoshi; Kyoko Iwao; Yuri Takahashi; Chiyomi Egawa; Shinzaburo Noguchi

Book ID
117466656
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
81 KB
Volume
159
Category
Article
ISSN
0304-3835

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Sporadic breast cancer in young women: P
Sporadic breast cancer in young women: Prevalence of loss of heterozygosity at p53, BRCA1 and BRCA2
✍ Suzanne M. Johnson; Jacqueline A. Shaw; Rosemary A. Walker πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 132 KB

## Abstract Previous studies have shown that breast cancers have more aggressive pathologic features in young women. In order to examine genetic alterations associated with early‐onset breast cancer, 31 patients with no known family history, aged 26–35 years at diagnosis, were examined for loss of