𝔖 Bobbio Scriptorium
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Absolute configuration and biological activity of viminol stereoisomers

✍ Scribed by D. Della Bella; G. Benelli; A. Sassi

Book ID
113199373
Publisher
Elsevier Science
Year
1976
Weight
747 KB
Volume
8
Category
Article
ISSN
0031-6989

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Absolute configuration and biological ac
Absolute configuration and biological activity of mequitamium iodide enantiomers
✍ Dr. Cristina Di Bugno; Paolo Dapporto; Raffaello Giorgi; Stefano Manzini; Paola πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 509 KB

## Abstract The enantiomers of 1‐methyl‐3‐(10__H__‐phenothiazine‐10‐ylmethyl)‐1‐azoniabicyclo[2,2,2]octane iodide (1) were prepared by chiral chromatographic resolution of the precursor mequitazine (2). The (+)‐(S)‐enantiomer 1b is 10‐fold more potent than (βˆ’)‐(R)‐enantiomer 1a as a histamine antag