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Absence of Significant Germ Line p53 Mutations in Ovarian Cancer Patients

✍ Scribed by Richard E. Buller; Jeffrey S. Skilling; Susan Kaliszewski; Theodore Niemann; Barrie Anderson

Book ID
115616638
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
383 KB
Volume
58
Category
Article
ISSN
0090-8258

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## Abstract Epidemiological studies on intracranial tumors have suggested that the observed familial aggregation of a proportion of gliomas may be due to inherited predisposition to their development. In the Li‐Fraumeni syndrome (LFS) associated with germ‐line mutations of the __p53__ gene, nervous