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Absence of Severe Systemic Toxicity After Leakage-Controlled Isolated Limb Perfusion With Tumor Necrosis Factor-α and Melphalan

✍ Scribed by Bart C. Vrouenraets; Bin B. R. Kroon; Aernout C. Ogilvie; Albert N. van Geel; Omgo E. Nieweg; Anton J. G. Swaak; Alexander M. M. Eggermont


Publisher
Springer
Year
1999
Tongue
English
Weight
94 KB
Volume
6
Category
Article
ISSN
1068-9265

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## Abstract ## BACKGROUND Since 1992, isolated limb perfusion (ILP) with tumor necrosis factor‐α (TNFα) and melphalan has been used for the treatment of patients with unresectable soft tissue sarcomas of the extremities. The authors retrospectively studied the results of limb salvage surgery using