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Absence of Prohibitin Gene Mutations in Human Epithelial Ovarian Tumors

โœ Scribed by W. Cliby; G. Sarkar; S.R. Ritland; L. Hartmann; K.C. Podratz; R.B. Jenkins


Book ID
115615876
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
234 KB
Volume
50
Category
Article
ISSN
0090-8258

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Loss of heterozygosity (LOH) on chromosome 10 is the most common genetic changes in glioblastomas of World Health Organization (WHO) Grade IV. [1][2][3][4][5][6][7] In most cases, the allelic losses involve loci along the entire chromosome, a finding in line with monosomy 10. LOH on chromosome 10 ma