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Absence of gene mutations in KIT-positive thymic epithelial tumors

โœ Scribed by Tsuchida, Masanori; Umezu, Hajime; Hashimoto, Takehisa; Shinohara, Hirohiko; Koike, Terumoto; Hosaka, Yasuko; Eimoto, Tadaaki; Hayashi, Jun-ich


Book ID
119319928
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
849 KB
Volume
62
Category
Article
ISSN
0169-5002

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Loss of heterozygosity (LOH) on chromosome 10 is the most common genetic changes in glioblastomas of World Health Organization (WHO) Grade IV. [1][2][3][4][5][6][7] In most cases, the allelic losses involve loci along the entire chromosome, a finding in line with monosomy 10. LOH on chromosome 10 ma