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DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer

✍ Scribed by Mok, S C; Chan, W Y; Wong, K K; Cheung, K K; Lau, C C; Ng, S W; Baldini, A; Colitti, C V; Rock, C O; Berkowitz, R S


Book ID
110061292
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
628 KB
Volume
16
Category
Article
ISSN
0950-9232

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## Abstract Allelic imbalance on chromosome arm 22q has been detected in 50–70% of ovarian cancers, suggesting the presence of a tumor‐suppressor gene on this chromosome arm that is involved in ovarian carcinogenesis. Recently, we isolated a candidate tumor‐suppressor gene, __MYO18B__, at 22q12.1,