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Absence of microsatellite instability in human chronic lymphocytic leukaemia B cells

✍ Scribed by Praz, F; Le Page, F; Vallat, L; Davi, F; Nguyen-Khac, F; Maloum, K; Delic, J; Merle-Béral, H

Book ID
110058398
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
141 KB
Volume
22
Category
Article
ISSN
0887-6924

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Sequential cytogenetic studies were performed on a minimum of two and a maximum of nine occasions (mean 3.6) on the peripheral blood leucocytes of 112 patients with B-CLL. On initial cytogenetic analysis, 58 had a normal karyotype and 64 had a clonal abnormality. Karyotypic evolution occurred in 18