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Aberrant peroxisome morphology in peroxisomal beta-oxidation enzyme deficiencies

✍ Scribed by Michinori Funato; Nobuyuki Shimozawa; Tomoko Nagase; Yasuhiko Takemoto; Yasuyuki Suzuki; Yoshihiko Imamura; Tadashi Matsumoto; Toshiro Tsukamoto; Tomoko Kojidani; Takashi Osumi; Toshiyuki Fukao; Naomi Kondo


Book ID
113498320
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
366 KB
Volume
28
Category
Article
ISSN
0387-7604

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Inhibition of peroxisomal beta-oxidation
✍ Christiane Van Den Branden; Georges Dacremont; Robert Hooghe; Frank Roels πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 608 KB

Thioridazine, an inhibitor of peroxisomal beta-oxidation, was administered orally to nursing rats during the period of maximal myelination in the pups (8-21 days postnatally). Under the experimental conditions, thioridazine causes accumulation of C24 and C26 fatty acids in pup brain lipids, an effec