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Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype

✍ Scribed by Shimura, Hanae; Mori, Naoki; Wang, Yan-Hua; Okada, Michiko; Motoji, Toshiko


Book ID
120540162
Publisher
Informa plc
Year
2012
Tongue
English
Weight
502 KB
Volume
53
Category
Article
ISSN
1042-8194

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Deregulated expression of the TAL1 gene
✍ Sylvie FranΓ§ois; Eric Delabesse; Laurence Baranger; Marie Dautel; Charles Foussa πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 239 KB πŸ‘ 1 views

TAL1 gene deregulation is frequent in T-cell acute lymphoblastic leukemia (T-ALL) and can result from translocations involving 1p32 or, more frequently, from a cytogenetically undetectable interstitial deletion of chromosome 1. This study presents a case of T-ALL with a t(1;5)(p32;q31) involving TAL