A versatile synthesis of retinoids via condensation of the side-chain to cyclic ketones
β Scribed by Fadila Derguini; Valeria Balogh-Nair; Koji Nakanishi
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 200 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Novel Nβterminusβtoβsideβchain cyclic analogs of the opioid peptide dynorphin (Dyn) Aβ(1β11)NH~2~ were prepared that retain the basicity of the Nβterminal amine and restrict the backbone conformation around the important Tyr^1^ residue. Cyclic peptides were synthesized in which the Nβte
Key steps of a new synthesis of the ZO-hydroxyecdysone side chain are (i) addition of 2 to ZO-ketopregnanes and (ii) the stereoselective reduction of the 22-keto group after OH group protection. PO-Hydroxyecdysone (IZb) plays a major regulatory role during the postembryonic development of insects an
Head-to-side-chain" cyclic tripeptides were designed as endothelin receptor antagonists. Solid phase synthesis of cyclic peptides, using an automated allyl cleavage procedure with Pd[P(Ph3)]a followed by cyclization was performed. Synthetic procedures were established on a continous-flow peptide syn
The b ynthu.b 06 the enanaXomehic&Yy puke m&n bide-chain .&A dedtibed &torn P-guLonok?actone.