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A unifying model of the immunoregulatory role of the interferon system: Can interferon produce disease in humans?

✍ Scribed by S. Skurkovich; B. Skurkovich; J.A. Bellanti


Book ID
118374850
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
947 KB
Volume
43
Category
Article
ISSN
1090-2341

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✍ Emily C Baechler; Peter K Gregersen; Timothy W Behrens πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 320 KB

Recent studies of patients with systemic lupus erythematosus, together with data from lupus-prone mice, suggest that inappropriate activation of type I interferon might have a role in disease pathogenesis. Serum levels of IFN-a are elevated in SLE patients, and gene expression profiling of periphera