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Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma

✍ Scribed by DeYoung, Katherine L; Ray, Michael E; Su, Yan A; Anzick, Sarah L; Johnstone, Ricky W; Trapani, Joseph A; Meltzer, Paul S; Trent, Jeffrey M


Book ID
110060811
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
611 KB
Volume
15
Category
Article
ISSN
0950-9232

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MACE-I has been identified as a human gene, which directs the expression of an antigen being recognized on melanoma cells by autologous cytolytic T cells. MACE-I is expressed in melanomas and some other tumors. It has been proposed that this gene may be linked to the transformation event and therefo