A Two-Step Synthesis of the Anticancer Drug (R,S)-Bicalutamide.
β Scribed by Kenneth D. James; Nnochiri N. Ekwuribe
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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Cytotrienin A (1) is a microbial antitumor secondary metabolite that was isolated from the fermentation broth of Streptomyces sp. RK95-74 from soil. [1] It possesses an E,E,E-triene motif within a 21-membered cyclic lactam, which also contains four chiral centers. These are common structural feature
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