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A total synthesis of aphidicolin

✍ Scribed by Trost, Barry M.; Nishimura, Yoshio; Yamamoto, Kagetoshi


Book ID
126863931
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
374 KB
Volume
101
Category
Article
ISSN
0002-7863

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πŸ“œ SIMILAR VOLUMES


A Total Synthesis of Aphidicolin: Stereo
✍ Rinaldo Marini Bettolo; Pietro Tagliatesta; Alessandro Lupi; Doriano Bravetti πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 German βš– 423 KB

## Abstract A simple, efficient, and stereospecific total synthesis of (Β±)‐3Ξ±, 18‐dihydroxy‐17‐noraphidicolan‐16‐one **(2)**, by solvolytic rearrangement of the __endo__‐bicyclo‐[2.2.2]oct‐5‐en‐2‐yl methanesulfonate **16**, is described. Since aphidicolin **(1)** has already been obtained from **2*

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