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A tetravalent anti-CD3-CD19 bispecific monoclonal antibody (mAb) has antitumour activity,


Book ID
120867723
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2000
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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A tumor vaccine containing anti-CD3 and
✍ Claudia Haas; Maria Lulei; Philippe Fournier; Annette Arnold; Volker Schirrmache πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 French βš– 636 KB

## Abstract We recently reported on newly designed virus‐targeted bispecific CD3‐ and CD28‐binding molecules for human T‐cell activation. When bound via one arm to a human virus‐modified tumor cell vaccine, these reagents caused a polyclonal T‐cell response and overcame the potential various T‐cell