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A technique for the isolation and mitogenic activation of thyroglobulin-specific human B lymphocytes

✍ Scribed by S.M. McLachlan; M.C. Atherton; S.L. Middleton; F. Clark; B. Rees Smith


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
370 KB
Volume
12
Category
Article
ISSN
0165-2478

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A monoclonal antibody (CB.l) is described that defines a new triggering signal for human cytotoxic T lymphocytes (CTL). The antibody precipitates a 103-kDa surface antigen from activated normal human T cells. The antigen is undetectable or present in only low amounts on resting T lymphocytes but its