The pattern of nuclease degradation observed for an antisense phosphorothioate oligonucleotide in pig kidney was determined using liquid chromatography/electrospray mass spectrometry (LC/ESI-MS) and LC/ESI-MS/MS with a quadrupole ion trap mass spectrometer. Metabolites were separated by length using
A tandem quadrupole-ion trap mass spectrometer
β Scribed by Kenneth L. Morand; Stevan R. Horning; R.Graham Cooks
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 674 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0168-1176
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