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Matrix-assisted Laser Desorption/Ionization Using a New Tandem Quadrupole Ion Storage Trap, Time-of-flight Mass Spectrometer

✍ Scribed by Peter Kofel; Markus Stöckli; Jörn Krause; Urs P. Schlunegger

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
581 KB
Volume
10
Category
Article
ISSN
0951-4198

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✦ Synopsis

A tandem quadrupole ion-storage trap, time-of-flight instrument using matrix-assisted laser desorptionl ionization has been constructed. Desorbed ions are lint trapped in an RF' field and collisionally relaxed prior to time-of-!light mass analysis. So far masses up to 90 kDa, a resolution of up to 700 and trapping times of up to 10 minutes have been measured with RF frequencies and amplitudes as low as 20 kHz and 40 V, respectively. The effects of pulse synchronization with the RF voltage and of extraction voltage variation on instrument performance have been investigated. Molecular ions of melittin have been found to undergo reactions in the gas phase during storage.

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