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A systematic review of phase II trials of thalidomide/dexamethasone combination therapy in patients with relapsed or refractory multiple myeloma

โœ Scribed by Marie Von Lilienfeld-Toal; Corinna Hahn-Ast; Kerstin Furkert; Florian Hoffmann; Ralph Naumann; Ralf Bargou; Gordon Cook; Axel Glasmacher


Book ID
114794450
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
204 KB
Volume
81
Category
Article
ISSN
0902-4441

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Phase II trial of temsirolimus in patien
โœ Sherif S. Farag; Shuhong Zhang; Buffy S. Jansak; Xiaojing Wang; Eric Kraut; Kenn ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 508 KB

In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat