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A systematic analysis of a flow-switching modulator for comprehensive two-dimensional gas chromatography

✍ Scribed by Russell W. LaClair; Pedro A. Bueno Jr.; John V. Seeley

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
785 KB
Volume
27
Category
Article
ISSN
1615-9306

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✦ Synopsis

Abstract

A simple flow‐switching device has been designed for use as a comprehensive two‐dimensional gas chromatography modulator. The device is constructed from fused silica tubing, t‐unions, and a solenoid valve. A series of experiments were conducted to determine the influence of primary flow, secondary flow, modulation time, and device dimensions on the performance of the modulator. The flow‐switching device was found to produce pulses with widths near the theoretical minimum. High‐performance was maintained over a wide range of modulation times. The flow‐switching device did not introduce extra broadening along the primary retention axis. However, the modulator performance was optimal only over a narrow range of primary to secondary flow ratios. The ideal flow ratio is determined by the dimensions of the tubes that connect the t‐unions. A simple flow resistance model has been developed that can predict the dimensions that will produce optimal results for a specified primary to secondary flow ratio. Thus, it is possible to construct a device that operates near the theoretical limit without numerous alterations. Under optimal conditions, the flow switching modulator generates peaks that are narrower than those produced by a diaphragm valve.

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