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A Synthetic Peptide Vaccine Involving the Product of the Pre-S(2) Region of Hepatitis B Virus DNA: Protective Efficacy in Chimpanzees

โœ Scribed by Yukio Itoh, Emiko Takai, Hitoshi Ohnuma, Kohji Kitajima, Fumio Tsuda, Atsuhiko Machida, Shunji Mishiro, Tetsuo Nakamura, Yuzo Miyakawa and Makoto Mayumi


Book ID
123633843
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
975 KB
Volume
83
Category
Article
ISSN
0027-8424

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A peptide was synthesized containing the entire 55 amino acid residue sequence of the hepatitis B virus (HBV) surface antigen preS2 region (ad subtype). The unconjugated peptide was inoculated into four chimpanzees. Following multiple injections, all of the animals developed specific antipeptide ant

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