A SYNTHETIC APPROACH TO THE AB-RING SYSTEM OF FORSKOLIN
โ Scribed by Kulkarni, Yashwant S.; Snider, Barry B.
- Book ID
- 121264564
- Publisher
- Taylor and Francis Group
- Year
- 1986
- Tongue
- English
- Weight
- 168 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0030-4948
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The functionalized tricyclic framework (XI) of the diterpene forskolin is synthesized by an intramolecular Diels-Alder reaction of the dienyne (VII), which is obtained by stereoselective introduction of the C side chains at C-1 and C-2 of tri-O-acetyl-D-galactal (I) via C-Ferrier and Claisen-Ireland
The syntksis of tk mkydic system offorskolin by an intramolecular DieleAidcr reaction is described, smrdng from tnQ9-acetyl-D-gakactai. Forskolln. a highly oxygenated labdane diterpcne, exhibits a broad range of physiological activities through its ability to activate adenylate cyclase. The therape