Stereoselective synthesis of hydroxy-ket
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Sylvie Tchertchian; Yannick VallΓ©e
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Article
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1998
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Elsevier Science
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French
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The reaction of Garner's aldehyde with dithioacetate enethiolates followed by alkylation of the intermediate aldolate gives hydroxy-ketenedithioacetals with a moderate anti selectivity. This methodology was applied to the synthesis of various other ketene dithioacetals with high E or Z stereoselecti