## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A survey of suitable protecting groups for the synthesis of hydroxylamines by Mitsunobu reactions
β Scribed by David W Knight; Mathew P Leese
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 60 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Boc-(R)-ot-phenylproline ethyl ester 1 was prepared in good yield starting from racemic phenylglycine. Condensation of phenylglycine ethyl ester with benzaldehyde furnished N-benzylidene phenylglycine ethyl ester which was allylated under phase transfer catalysis conditions. After acidic hydrolysis,
Use of dimethylphosphinyl (Dmp) group as a side-chain phenolic OH protecting group of tyrosine in peptide synthesis was studied. The Dmp group is resistant to trifluoroacetic acid and hydrogenolysis and removed by fluoride ion or liquid HF. The formation of 3-benzyltyrosine from e-benzyl tyrosine in
The 1-~(2-chloro-4-methyl)phenyl]-4-methoxypiperidin-4-yl [Ctmp, as in (14a)] has an acid lability similar to that of the 4-methoxytetrahydropyran-4-yl (Mthp) protect= group under mild hydrolytic conditions [pH 2-31; however, under the relatively more drastic conditions required for the complete rem