A study of cultured fetal and SV40-transformed Chinese hamster Kupffer cells
β Scribed by J.M. Clark; J.A. Pateman
- Book ID
- 118877207
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 833 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
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## Abstract Amplification of SV40 genes in SV40βtransformed Chinese hamster embryo cells (CO631) by chemical carcinogens as well as by herpes simplex virus infection can be inhibited by infection with the defective parvovirus, AAVβ5. This is shown by __in situ__ hybridization with SV40 DNA of AAVβ5
## Abstract Infection with Herpes simplex viruses (HSV) induces amplification of SV40 sequences in SV40βtransformed Chinese hamster embryo cells (CO631). This is shown by __in situ__ hybridization of the infected cells with cloned ^32^Pβlabelled SV40 DNA. The HSVβmediated synthesis of SV40 DNA is m