Selective killing of carcinogen-treated SV40-transformed Chinese hamster cells by a defective parvovirus

Inhibition of initiator-induced SV40 gen

Inhibition of initiator-induced SV40 gene amplification in SV40-transformed Chinese hamster cells by infection with a defective parvovirus

✍ Jörg R. Schlehofer; Regine Heilbronn; Brigitte Georg-Fries; Harald Zur Hausen 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 469 KB 👁 1 views

## Abstract Amplification of SV40 genes in SV40‐transformed Chinese hamster embryo cells (CO631) by chemical carcinogens as well as by herpes simplex virus infection can be inhibited by infection with the defective parvovirus, AAV‐5. This is shown by __in situ__ hybridization with SV40 DNA of AAV‐5