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A straightforward preparation of amino–polystyrene resin from Merrifield resin

✍ Scribed by Stellios Arseniyadis; Alain Wagner; Charles Mioskowski

Book ID
104252359
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
104 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

Azidomethyl-polystyrene, obtained by nucleophilic substitution of chloromethyl-polystyrene, undergoes a Schmidt rearrangement when treated with trifluoromethanesulfonic acid, affording amino-polystyrene. To assess its loading and reactivity the resin is used as a support for the preparation of triazene-linked amine.

📜 SIMILAR VOLUMES

A rapid method for the preparation of am
A rapid method for the preparation of amino acid resin esters for merrifield solid-phase peptide synthesis
✍ Michael W. Monahan; Chaim Gilon 📂 Article 📅 1973 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 389 KB 👁 2 views

## Abstract An improved method for the preparation of Merrifield resin esters is presented. This method is rapid, is free of racemization, and is not complicated by a quaternization side reaction. Chloromethylated resin beads, __t__‐butoxycarbonyl amino acid, and potassium __t__‐butoxide are heated