Although the photochemistry of a,S-unsaturated ketones has been extensively explored, (1) few data ara available on the photolytic reactions of aliphatic non-conjuSated olefinic ketones.(2) We becsms particularly
A stereospecific synthesis of 4-oxo-2trans-hexenal
β Scribed by J. P. Ward; D. A. van Dorp
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 238 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0165-0513
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π SIMILAR VOLUMES
with the DessNartin periodinane (1) in fluorotrichloromethane (freon 11). Use of the freon solvent greatly improved the recovery of this volatile aldehyde. Similarly the oxidation of 3,4-2Hz-3Z-hexen-1-ol (5) yielded 3,4-'HZ- 3Z-hexenal (6) in a 92% isolated yield with a purity of greater than 99%.
The stereospecific synthesis of trans-1,3-disubstituted-1,2,3,4\_tetrahydro $-carbolines has been accomplished in good yield by a two step sequence which involves Pi&et-Spengler condensation of Nb-benzyltryptophan methyl: ester with aldehydes, followed by removal of the 2-benzyl moiety from the corr