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A stereoselective synthesis of 8(R) and 8(S),11(R),12(S)-trihydroxyeicosa-5(Z),9(E),14(Z)-trienoic acid from 2-deoxy-D-ribose

โœ Scribed by J.S. Yadav; Prahlad Vadapalli


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
260 KB
Volume
35
Category
Article
ISSN
0040-4039

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An efficient and simple total synthesis of the two C(8) diastereomers of 2, of interest as possible hormonal releasing agents, is described. A previous publication from this laboratory has described the synthesis of the two diastereomeric lo-hydroxy-11, lZ(S, S)-epoxyeicosa-5,9,14(Z)-trienoic acids