𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A stereocontrolled synthesis of (−)-bestatin from an acyclic allylamine by iodocyclocarbamation

✍ Scribed by Susumu Kobayashi; Toshiyuki Isobe; Masaji Ohno

Book ID
104242316
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
227 KB
Volume
25
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

1,2-Asymmetric induction of iodocyclocarbamation is described by using allylamines 2 and 6 and the method has been successfully applied to a stereocontrolled synthesis of bestatin.

📜 SIMILAR VOLUMES

Stereocontrolled synthesis of 6-epi-D-pu
Stereocontrolled synthesis of 6-epi-D-purpurosamine B by iodocyclocarbamation of a chiral Z-olefin derived from L-alanine and L-malic acid
✍ Keiji Kamiyama; Yasuharu Urano; Susumu Kobayashi; Masaji Ohno 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 269 KB

6-epi-D-Purpurosamine B was synthesized efficiently through a chiral Z-olefin 8 derived from L-alanine and L-malic acid under complete stereochemical control by using iodocyclocarbamation as the key reaction.