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A Stepwise One-Pot Synthesis of Alkyl Thiophosphoramidate Derivatives of Nucleosides.

✍ Scribed by Zhi-Wei Miao; Hua Fu; Bo Han; Yi Chen; Yu-Fen Zhao

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
33
Category
Article
ISSN
0931-7597

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## Abstract Novel aryl N‐phosphonamidothionate derivatives of nucleosides as membrane‐soluble prodrugs of bioactive free nucleotides have been prepared by phosphochloridothioate chemistry. Unprotected nucleosides, for example uridine and adenosine, were used; phosphorylation took place selectively

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v