It has been shown that an appreciable percentage of patients presenting with primary, apparently sporadic phaeochromocytomas may in fact have von-Hippel-Lindau (VHL) disease. In order to investigate this, we retrospectively screened 68 patients, who had been operated on for phaeochromocytomas, for t
✦ LIBER ✦
A specific germline mutation in the VHL tumor suppressor gene correlates with pheochromocytoma
✍ Scribed by H. Brauch; T. Kishida; D. Glavac; F. Pausch; B. Zbar; M.I. Lerman; H. Höfler; H.P.H. Neumann
- Book ID
- 113253805
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 161 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0165-4608
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Communicated by Victor A. McKusick von Hippel-Lindau disease (VHL) is an inherited neoplastic disorder characterized by the development of tumors in the eyes, brain, spinal cord, inner ear, adrenal gland, pancreas, kidney, and epididymis. The VHL tumor suppressor gene was identified in 1993. Initial
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