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A simple synthesis of novel 2-pyridones from chalcones

โœ Scribed by Mohammad M. Al-Arab

Book ID
112129554
Publisher
Journal of Heterocyclic Chemistry
Year
1990
Tongue
English
Weight
239 KB
Volume
27
Category
Article
ISSN
0022-152X

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Heterocyclic 4-sulfonyl-2-pyridones represent useful scaffolds for drug discovery and are also versatile synthetic building blocks. Herein we describe a novel and efficient synthesis of this heterocyclic ring system utilizing an acid mediated cyclo-condensation reaction. This synthetic method afford