Palladium-Catalyzed Asymmetric Allylic A
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Barry M. Trost; Gretchen M. Schroeder
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Article
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2005
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John Wiley and Sons
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English
β 390 KB
## Abstract Palladiumβcatalyzed asymmetric allylic alkylation of nonstabilized ketone enolates to generate quaternary centers has been achieved in excellent yield and enantioselectivity. Optimized conditions consist of performing the reaction in the presence of two equivalents of LDA as base, one e