A five step synthesis of (d,l)-estrane d
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Pierre- Yves Michellys; Hélène Pellissier; Maurice Santelli
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Article
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1993
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Elsevier Science
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French
⚖ 234 KB
A spidamne 2. obtained in two steps from 1.3-butadiene (ca 50 Q). was metho~ycdonylated GHMDS I dimethykarbonate) and akylated wilh idobenzoc+butene (K2CO3 / acetone) to give 8. Heating of I3 kd to the esuane derivative 9 with 6 contnAled centers. The overall yield from I .3-butediene was ca. 32 46.