Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has been used as a rapid method for the detection of human genetic polymorphisms. In particular, the mutations in the human HEXA gene that cause the infantile Tay-Sachs disease have been studied using MALDI-MS to demonstrate th
A simple and rapid matrix-assisted laser desorption/ionization time of flight mass spectrometry method to screen fish plasma samples for estrogen-responsive biomarkers
โ Scribed by Kimberly A. Salinas; Michael J. Hemmer; Peggy S. Harris; Calvin C. Walker
- Book ID
- 111848769
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 372 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0730-7268
- DOI
- 10.1897/07-226.1
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Rapid methods using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry to monitor recombinant protein expression from various prokaryotic and eukaryotic cell culture systems were devised. Intracellular as well as secreted proteins from both induced and constitutive expressi