A Simple and Efficient Method for the Resolution of All Four Diastereomers of 4,4,4-Trifluorovaline and 5,5,5-Trifluoroleucine.
β Scribed by Xing, Xuechao; Fichera, Alfio; Kumar, Krishna
- Book ID
- 111947666
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 20 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A simple procedure for the synthesis and further functionalization of 4,5-diaminopyrazoles using mild conditions is reported herein. The desired products were obtained in good yield, and the structures have been confirmed by X-ray crystallography.
## Abstract magnified image Synthesis of novel isoxazolyl 1,3,5βbenzoxadiazocines **5** has been accomplished by condensation of 3βaminoβ5βmethylisoxazole **1** with salicylaldehydes, followed by reduction, treatment with arylisothiocyanates, and subsequent ring closure in the presence of formalde