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A Simple and Direct Synthesis of Erythro‐β‐amino‐α‐hydroxy Esters from trans ‐β‐Phenylglycidic Ester

✍ Scribed by Besbes, Rafâa; Ennigrou, Mohamed Rached


Book ID
121346610
Publisher
Taylor and Francis Group
Year
2004
Tongue
English
Weight
169 KB
Volume
34
Category
Article
ISSN
0039-7911

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Synthesis of β-amino α-hydroxy carboxyli
✍ Johan Legters; Erik van Dienst; Lambertus Thijs; Binne Zwanenburg 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 716 KB

## Abstract 3‐Aryl‐3‐azido‐2‐hydroxypropanoic esters, prepared from the corresponding 3‐aryl‐oxirane‐2‐carboxylic esters by ring opening with sodium azide, were reduced with tin(II) chloride dihydrate in methanol to give 3‐amino‐3‐aryl‐2‐hydroxypropanoic esters in good yields. Under these condition