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A simple and convenient method for the preparation of α-substituted-α-diazoesters

✍ Scribed by Noro Takamura; Tomishige Mizoguchi; Kenji Koga; Shun-ichi Yamada

Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
196 KB
Volume
12
Category
Article
ISSN
0040-4039

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✦ Synopsis

The first synthesis of diazoesters by direct diazotization of amino acid esters was reported by Curtius I,*) around 1900. Although this method is well suited for the preparation of diazoacetic ester, 3) it is generally inapplicable to the syntheses of a-substituted-a-diazoesters (I),*) because of very low yields * To whom inquiries may be addressed.

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