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A silver(i)-catalyzed tandem reaction of 2-alkynylbenzaldoximes with ketenes

✍ Scribed by Liu, Hongliang; Liu, Gang; Pu, Shouzhi; Wang, Zhiyong


Book ID
120196364
Publisher
Royal Society of Chemistry
Year
2013
Tongue
English
Weight
989 KB
Volume
11
Category
Article
ISSN
1477-0520

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## Abstract 2‐Alkynylbenzaldoximes react with carbodiimides under mild conditions and silver triflate catalysis in DMF, leading to a diverse range of 1‐(isoquinolin‐1‐yl)ureas in good to excellent yields. This transformation involves tandem 6‐__endo__ cyclization, [3+2] cycloaddition, and subsequen