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A Silver(I)-Catalyzed Tandem Reaction of 2-Alkynylbenzaldoxime with Alkylidenecyclopropane

✍ Scribed by Xiao, Qian; Ye, Shengqing; Wu, Jie


Book ID
118048083
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
603 KB
Volume
14
Category
Article
ISSN
1523-7060

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## Abstract 2‐Alkynylbenzaldoximes react with carbodiimides under mild conditions and silver triflate catalysis in DMF, leading to a diverse range of 1‐(isoquinolin‐1‐yl)ureas in good to excellent yields. This transformation involves tandem 6‐__endo__ cyclization, [3+2] cycloaddition, and subsequen