A short synthesis of 5-amino[4-14]laevul
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J B Cambell; J S Johnston
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Article
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1989
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John Wiley and Sons
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French
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## 5-Amin0[4-'~C]laevulinic acid hydrochloride has been prepared from potassium [14C]cyanide in 56% overall yield. The key step is the palladium[O] catalysed coupling of 2-phthalimid0[l-'~C]acetyl chloride with 2-carboethoxyethylzinc iodide to give 5-phthalimid0[4-'~C]laevulinic acid ethyl ester i