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A short, stereospecific synthesis of dihydrooxazoles from serine and threonine derivatives

✍ Scribed by Peter Wipf; Chris P. Miller

Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
268 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis

Cyclization of serine and threonine derivatives with Burgess reagent provides a one-step, stereospecific access to 45dihydrooxazoles.

Noteworthy features of this new methodology include mild experimental conditions, and the absence of p-lactam. aziridine. or dehydroamino acid side products.

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