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A short and simple synthesis of the thioglucose analog of the antitumor agent etoposide

✍ Scribed by Pietro Allevi; Mario Anastasia; Pierangela Ciuffreda


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
219 KB
Volume
32
Category
Article
ISSN
0040-4039

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Structure, synthesis, and antitumor acti
✍ Wayne K. Anderson; D. Michael Houston; Mark A. Jarosinski; Frederick R. Kinder J πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 338 KB πŸ‘ 1 views

## Abstract The two isomeric monocarbamates, 2b and 2c, related to the antitumor drug carmethizole (1) were synthesized and the structure of the carmethizole hydrolysis product, 2b, was established by X‐ray crystallography. The chemical reactivity, toxicity, and antitumor activity of the two monoca