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A Sensitive and Reliable Assay for Dopamine (β-Hydroxylase in Tissue

✍ Scribed by Günther Sperk; Ingrid Galhaup; Elisabeth Schlögl; Heide Hörtnagl; Oleh Hornykiewicz


Book ID
111170990
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
440 KB
Volume
35
Category
Article
ISSN
0022-3042

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A simple and sensitive assay for dopamin
✍ Tong Hyub Joh; Robert A. Ross; Donald J. Reis 📂 Article 📅 1974 🏛 Elsevier Science 🌐 English ⚖ 349 KB

A simple, rapid, and highly sensitive radiochemical assay for measuring the activity of dopamine+hydroxylase in tissues and serum is described. Enzyme activity is detected by converting [l-'"Cltyramine to [l-"Cloctopamine which is then subjected to periodate cleavage to form ["Clformamide. This radi