A Ruthenium-Catalyzed Approach to the Friedländer Quinoline Synthesis
✍ Scribed by Hans Vander Mierde; Pascal Van Der Voort; Dirk De Vos; Francis Verpoort
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 197 KB
- Volume
- 2008
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract Novel quinolines fused with a six‐member ring **5a–j** were prepared in high yields (75–95%) via the Friedländer reaction of dimethoxy‐substituted __o__‐aminobenzaldehydes of **3a** or **3b** with cyclic ketones **4**, respectively. The structures of **5a–j** were determined by IR, ^1^H
## Abstract Lewis acidic ionic liquid is shown to be for the first time an excellent medium and efficient catalyst for the synthesis of quinolines at room temperature from __o__‐amino aromatic carbonyls and ketones containing active methylene group.