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A mild, efficient and improved protocol for the friedländer synthesis of quinolines using lewis acidic ionic liquid

✍ Scribed by Ganesan Karthikeyan; Paramasivan T. Perumal

Publisher
Journal of Heterocyclic Chemistry
Year
2004
Tongue
English
Weight
48 KB
Volume
41
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Lewis acidic ionic liquid is shown to be for the first time an excellent medium and efficient catalyst for the synthesis of quinolines at room temperature from o‐amino aromatic carbonyls and ketones containing active methylene group.

📜 SIMILAR VOLUMES

Friedländer synthesis of poly-substitute
Friedländer synthesis of poly-substituted quinolines in the presence of triethylammonium hydrogen sulfate [Et3NH][HSO4] as a highly efficient, and cost effective acidic ionic liquid catalyst
✍ Esmat Tavakolinejad Kermani; Hojatollah Khabazzadeh; Tayebeh Jazinizadeh 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 105 KB

## Abstract A rapid and an efficient method for the preparation of a variety of substituted quinolines has been developed through the reactions of __o__‐aminoarylketones with carbonyl compounds containing a reactive α‐methylene moiety in the presence of molten [Et~3~NH][HSO~4~] under solvent‐free c