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Efficient synthesis of novel six-member ring-fused quinoline derivatives via the friedländer reaction

✍ Scribed by Dingqiao Yang; Wei Guo; Yuepeng Cai; Lasheng Jiang; Kailing Jiang; Xiaobing Wu

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
137 KB
Volume
19
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

Novel quinolines fused with a six‐member ring 5a–j were prepared in high yields (75–95%) via the Friedländer reaction of dimethoxy‐substituted o‐aminobenzaldehydes of 3a or 3b with cyclic ketones 4, respectively. The structures of 5a–j were determined by IR, ^1^H NMR, MS, and elemental analysis. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:229–233, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20356

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